Endocrine Abstracts

Introduction: Non-alcoholic fatty liver disease (NAFLD) is a common cause of impaired liver functions. It is associated with hepatic and adipose tissue insulin resistance (IR) as well as decreased whole-body insulin sensitivity. Thyroid hormones are important for the intrahepatic metabolism of lipids. Thyroid disorders have been associated with IR due to various mechanisms such as altered insulin secretion and lipid levels.Aim: The aim of our study was t...

Introduction: Hypothyroidism is associated with increased risk of atherosclerosis. We assessed both carotid intima media thickness (CIMT), as a marker of atherosclerosis, and endothelial dysfunction in patients with hypothyroidism.Methods: We included 70 female patients with hypothyroidism (age 18–55 years), 40 patients with overt and 30 patients with subclinical hypothyroidism (SCH). Forty age and sex matched subjects with normal thyroid functions ...

Disorders of sex development create medical and social dilemma. Maleness with XX genotype is a rare genetic condition affecting one in 24,000 new-born males. Characterized by a spectrum of clinical presentation, ranging from normal male genitalia to ambiguous sex.Case report: A 31 years old patient with ambiguous genitalia raised as a male. He came to our endocrinology clinic to stabilize his male identity by surgical correction, no parental consanguinit...

Background and aim: The normal range of thyroid functions during pregnancy differs between ethnic groups. The aim of this work was to assess the thyroid functions in normal pregnant Egyptian females in order to establish a population-specific reference range. Thyroid peroxidase antibodies (TPO Abs) and thyroid volume were also assessed.Methods: The study included 150 normal pregnant Egyptian females (with no history suggestive of thyroid...